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Targeting HDACs: A Promising Therapy for Alzheimer's Disease
Epigenetic modifications like DNA methylation and histone acetylation play an important role in a wide range of brain disorders. Histone deacetylases (HDACs) regulate the homeostasis of histone acetylation. Histone deacetylase inhibitors, which initially were used as anticancer drugs, are recently s...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Hindawi Publishing Corporation
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177096/ https://ncbi.nlm.nih.gov/pubmed/21941604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/143269 |
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