Nonkinetic Modeling of the Mechanical Unfolding of Multimodular Proteins: Theory and Experiments

We introduce and discuss a novel approach called back-calculation for analyzing force spectroscopy experiments on multimodular proteins. The relationship between the histograms of the unfolding forces for different peaks, corresponding to a different number of not-yet-unfolded protein modules, is ex...

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Hlavní autoři: Benedetti, F., Micheletti, C., Bussi, G., Sekatskii, S.K., Dietler, G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
Spectroscopy, Imaging, and Other Techniques
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177077/
https://ncbi.nlm.nih.gov/pubmed/21943432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.047
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