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KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition
Voltage-gated potassium (Kv) currents generated by N-type α-subunit homotetramers inactivate rapidly because an N-terminal ball domain blocks the channel pore after activation. Hence, the inactivation rate of heterotetrameric channels comprising both N-type and non-N-type (delayed rectifier) α-subun...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177048/ https://ncbi.nlm.nih.gov/pubmed/21943417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.014 |
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