KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition

Voltage-gated potassium (Kv) currents generated by N-type α-subunit homotetramers inactivate rapidly because an N-terminal ball domain blocks the channel pore after activation. Hence, the inactivation rate of heterotetrameric channels comprising both N-type and non-N-type (delayed rectifier) α-subun...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kanda, Vikram A., Lewis, Anthony, Xu, Xianghua, Abbott, Geoffrey W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2011
Gaiak:
Channels and Transporters
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177048/
https://ncbi.nlm.nih.gov/pubmed/21943417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.014
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