EPITHELIAL MESENCHYMAL TRANSITION AND HEDGEHOG SIGNALING ACTIVATION ARE ASSOCIATED WITH CHEMORESISTANCE AND INVASION OF HEPATOMA SUBPOPULATIONS

BACKGROUND & AIMS: Our previous studies showed that CD133, EpCAM and aldehyde dehydrogenase (ALDH) are useful markers to identify cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) tissues. The present study aims to evaluate chemosensitivity and invasion capability of HCC based on CSC ma...

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Autori principali: Chen, Xiaoli, Lingala, Shilpa, Khoobyari, Shiva, Nolta, Jan, Zern, Mark A., Wu, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177032/
https://ncbi.nlm.nih.gov/pubmed/21334406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.12.043
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