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Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity.

We have isolated from human liver libraries two cytochrome P450 cDNA clones (lambda MP14 and lambda MP3) which are highly similar (83% over the coding region) to mouse testosterone 15 alpha hydroxylase and are therefore part of the cytochrome P450IIA gene subfamily. The P450IIA (CYP2A) gene subfamil...

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Autors principals: Miles, J S, Bickmore, W, Brook, J D, McLaren, A W, Meehan, R, Wolf, C R
Format: Artigo
Idioma:Inglês
Publicat: 1989
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317701/
https://ncbi.nlm.nih.gov/pubmed/2726448
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