Differential Outcomes in Pre-diabetic vs. Overtly Diabetic NOD Mice Nonmyeloablatively Conditioned with Co-stimulatory Blockade

OBJECTIVE: Autoimmune diabetes can be reversed with mixed chimerism. However, the myelotoxic agents currently required to establish chimerism have prevented the translation of this approach to the clinic. Here, we investigated whether multimodal co-stimulatory blockade would enhance chimerism and pr...

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Hlavní autoři: Bozulic, Larry D., Huang, Yiming, Xu, Hong, Wen, Yujie, Ildstad, Suzanne T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176996/
https://ncbi.nlm.nih.gov/pubmed/21726515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.06.008
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