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The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding

Suspension animal cell culture is now routinely scaled up to bioreactors on the order of 10,000 L, and greater, to meet commercial demand. However, the concern of the ‘shear sensitivity’ of animal cells still remains, not only within the bioreactor, but also in the downstream processing. As the prod...

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Detalhes bibliográficos
Main Authors: Hu, Weiwei, Berdugo, Claudia, Chalmers, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176934/
https://ncbi.nlm.nih.gov/pubmed/21785843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-011-9368-3
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