Loss of function studies in mice and genetic association link receptor protein tyrosine phosphatase α to schizophrenia

BACKGROUND: Solid evidence links schizophrenia (SZ) susceptibility to neurodevelopmental processes involving tyrosine phosphorylation-mediated signaling. Mouse studies implicate the Ptpra gene, encoding protein tyrosine phosphatase RPTPα, in the control of radial neuronal migration, cortical cytoarc...

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Main Authors: Takahashi, Nagahide, Nielsen, Karin Sandager, Aleksic, Branko, Petersen, Steffen, Ikeda, Masashi, Kushima, Itaru, Vacaresse, Nathalie, Ujike, Hiroshi, Iwata, Nakao, Dubreuil, Véronique, Mirza, Naheed, Sakurai, Takeshi, Ozaki, Norio, Buxbaum, Joseph D., Sap, Jan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176920/
https://ncbi.nlm.nih.gov/pubmed/21831360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.06.016
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