Common Alzheimer's Disease Risk Variant Within the CLU Gene Affects White Matter Microstructure in Young Adults

There is a strong genetic risk for late-onset Alzheimer's disease (AD), but so far few gene variants have been identified that reliably contribute to that risk. A newly confirmed genetic risk allele C of the clusterin (CLU) gene variant rs11136000 is carried by ∼88% of Caucasians. The C allele...

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Huvudupphovsmän: Braskie, Meredith N., Jahanshad, Neda, Stein, Jason L., Barysheva, Marina, McMahon, Katie L., de Zubicaray, Greig I., Martin, Nicholas G., Wright, Margaret J., Ringman, John M., Toga, Arthur W., Thompson, Paul M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176803/
https://ncbi.nlm.nih.gov/pubmed/21543606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5794-10.2011
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