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Resolution of Praziquantel

BACKGROUND: Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsibl...

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Autores principales: Woelfle, Michael, Seerden, Jean-Paul, de Gooijer, Jesse, Pouwer, Kees, Olliaro, Piero, Todd, Matthew H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176743/
https://ncbi.nlm.nih.gov/pubmed/21949890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001260
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