GLUTATHIONYLATION OF PEROXIREDOXIN I INDUCES DECAMER TO DIMERS DISSOCIATION WITH CONCOMITANT LOSS OF CHAPERONE ACTIVITY

Reversible protein glutathionylation, a redox-sensitive regulatory mechanism, plays a key role in cellular regulation and cell signaling. Peroxiredoxins (Prxs), a family of peroxidases that is involved in removing H(2)O(2) and organic hydroperoxides, are known to undergo a functional change from per...

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Main Authors: Park, Ji Won, Piszczek, Grzegorz, Rhee, Sue Goo, Chock, P. Boon
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176717/
https://ncbi.nlm.nih.gov/pubmed/21401077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101373h
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