Melanocortin 4 Receptor Activation Protects Against Testicular Ischemia-Reperfusion Injury by Triggering the Cholinergic Antiinflammatory Pathway

Melanocortins (MC) trigger a vagus nerve-mediated cholinergic-antiinflammatory pathway projecting to the testis. We tested whether pharmacological activation of brain MC receptors might protect the testis from the damage induced by ischemia-reperfusion. Adult male rats were subjected to 1-h testicul...

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Detalhes bibliográficos
Main Authors: Minutoli, Letteria, Bitto, Alessandra, Squadrito, Francesco, Irrera, Natasha, Rinaldi, Mariagrazia, Nicotina, Piero Antonio, Arena, Salvatore, Magno, Carlo, Marini, Herbert, Spaccapelo, Luca, Ottani, Alessandra, Giuliani, Daniela, Romeo, Carmelo, Guarini, Salvatore, Antonuccio, Pietro, Altavilla, Domenica
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Neuroendocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176654/
https://ncbi.nlm.nih.gov/pubmed/21828180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1016
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