PPARγ-Independent Increase in Glucose Uptake and Adiponectin Abundance in Fat Cells

Although thiazolidinediones (TZD) effectively improve hyperglycemia and increase adiponectin, a proinsulin-sensitizing adipokine, they also increase adipogenesis via peroxisome proliferator-activated receptor (PPAR)γ induction, which may be undesirable. Recent safety concerns about some TZD have pro...

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Detalhes bibliográficos
Main Authors: Dubuisson, Olga, Dhurandhar, Emily J., Krishnapuram, Rashmi, Kirk-Ballard, Heather, Gupta, Alok K., Hegde, Vijay, Floyd, Elizabeth, Gimble, Jeffrey M., Dhurandhar, Nikhil V.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176641/
https://ncbi.nlm.nih.gov/pubmed/21791563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-0225
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