Insulin/IGF-I Regulation of Necdin and Brown Adipocyte Differentiation Via CREB- and FoxO1-Associated Pathways

Brown adipose tissue plays an important role in obesity, insulin resistance, and diabetes. We have previously shown that the transition from brown preadipocytes to mature adipocytes is mediated in part by insulin receptor substrate (IRS)-1 and the cell cycle regulator protein necdin. In this study,...

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Autori principali: Cypess, Aaron M., Zhang, Hongbin, Schulz, Tim J., Huang, Tian Lian, Espinoza, Daniel O., Kristiansen, Karsten, Unterman, Terry G., Tseng, Yu-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
Soggetti:
Energy Balance-Obesity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176640/
https://ncbi.nlm.nih.gov/pubmed/21862615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1229
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