Insulin/IGF-I Regulation of Necdin and Brown Adipocyte Differentiation Via CREB- and FoxO1-Associated Pathways

Brown adipose tissue plays an important role in obesity, insulin resistance, and diabetes. We have previously shown that the transition from brown preadipocytes to mature adipocytes is mediated in part by insulin receptor substrate (IRS)-1 and the cell cycle regulator protein necdin. In this study,...

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Bibliografiske detaljer
Main Authors: Cypess, Aaron M., Zhang, Hongbin, Schulz, Tim J., Huang, Tian Lian, Espinoza, Daniel O., Kristiansen, Karsten, Unterman, Terry G., Tseng, Yu-Hua
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2011
Fag:
Energy Balance-Obesity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176640/
https://ncbi.nlm.nih.gov/pubmed/21862615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1229
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