N-acetyl Cysteine Treatment Rescues Cognitive Deficits Induced by Mitochondrial Dysfunction in G72/G30 Transgenic Mice

Genetic studies have implicated the evolutionary novel, anthropoid primate-specific gene locus G72/G30 in psychiatric diseases. This gene encodes the protein LG72 that has been discussed to function as a putative activator of the peroxisomal enzyme -amino-acid-oxidase (DAO) and as a mitochondrial pr...

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Detalhes bibliográficos
Main Authors: Otte, David-Marian, Sommersberg, Britta, Kudin, Alexei, Guerrero, Catalina, Albayram, Önder, Filiou, Michaela D, Frisch, Pamela, Yilmaz, Öznur, Drews, Eva, Turck, Christoph W, Bilkei-Gorzó, Andras, Kunz, Wolfram S, Beck, Heinz, Zimmer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176560/
https://ncbi.nlm.nih.gov/pubmed/21716263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.109
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