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Peptidoglycan Recognition Proteins kill bacteria by inducing suicide through protein-sensing two-component systems

Mammalian Peptidoglycan Recognition Proteins (PGRPs), similar to antimicrobial lectins, bind to bacterial cell wall and kill bacteria through an unknown mechanism. We show that PGRPs enter Gram-positive cell wall at the site of daughter cell separation during cell division. In Bacillus subtilis PGRP...

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Detalhes bibliográficos
Main Authors: Kashyap, Des Raj, Wang, Minhui, Liu, Li-Hui, Boons, Geert-Jan, Gupta, Dipika, Dziarski, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176504/
https://ncbi.nlm.nih.gov/pubmed/21602801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2357
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