Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a debilitating, progressive joint disease. METHODS: Similar to the disease progression in humans, sequential events of early cartilage degradation, subchondral osteopenia followed by sclerosis, and late osteophyte formation were demonstrated in the anterior cruciat...

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Hauptverfasser: Pickarski, Maureen, Hayami, Tadashi, Zhuo, Ya, Duong, Le T
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176489/
https://ncbi.nlm.nih.gov/pubmed/21864409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-197
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