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Mechanical Coupling Between Myofibroblasts and Cardiomyocytes Slows Electrical Conduction in Fibrotic Cell Monolayers

BACKGROUND: Following cardiac injury, activated cardiac myofibroblasts can influence tissue electrophysiology. Because mechanical coupling through adherens junctions provides a route for intercellular communication, we tested the hypothesis that myofibroblasts exert tonic contractile forces on the c...

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Autors principals: Thompson, Susan A., Copeland, Craig R., Reich, Daniel H., Tung, Leslie
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176459/
https://ncbi.nlm.nih.gov/pubmed/21537003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.015057
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