Polo-like Kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer

Polo-like kinase 1 (PLK1) is overexpressed in various human cancers. However, the biological functions and the post-transcriptional regulations of PLK1 in esophageal cancer (EC) are still unknown. The purposes of this study are to determine whether PLK1 can be a molecular target of EC therapy, and t...

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Bibliographische Detailangaben
Hauptverfasser: Ito, Tetsuo, Sato, Fumiaki, Kan, Takatsugu, Cheng, Yulan, David, Stefan, Agarwal, Rachana, Paun, Bogdan C., Jin, Zhe, Olaru, Alexandru V., Hamilton, James P., Selaru, Florin M., Yang, Jian, Matsumura, Nobutoshi, Shimizu, Kazuharu, Abraham, John M., Shimada, Yutaka, Mori, Yuriko, Meltzer, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176391/
https://ncbi.nlm.nih.gov/pubmed/21170987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25874
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