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A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests

BACKGROUND: Allergic contact dermatitis is an inflammatory skin disease that affects a significant proportion of the population. This disease is caused by an adverse immune response towards chemical haptens, and leads to a substantial economic burden for society. Current test of sensitizing chemical...

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Bibliographische Detailangaben
Hauptverfasser: Johansson, Henrik, Lindstedt, Malin, Albrekt, Ann-Sofie, Borrebaeck, Carl AK
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176258/
https://ncbi.nlm.nih.gov/pubmed/21824406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-399
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