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RIC8 Is a Guanine-Nucleotide Exchange Factor for Gα Subunits That Regulates Growth and Development in Neurospora crassa

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits. Recently, facilitated GDP/GTP exchange by non-GPCR GEFs, such as RIC8, has emerged as an important...

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Bibliographic Details
Main Authors: Wright, Sara J., Inchausti, Regina, Eaton, Carla J., Krystofova, Svetlana, Borkovich, Katherine A.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176126/
https://ncbi.nlm.nih.gov/pubmed/21750256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.129270
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