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Sclera-Choroid-RPE Transport of Eight β-Blockers in Human, Bovine, Porcine, Rabbit, and Rat Models

PURPOSE. To determine the influence of drug lipophilicity, ocular pigmentation, and species differences on transscleral solute transport. METHODS. The transport of eight β-blockers across excised sclera/sclera-choroid-RPE (SCRPE) of albino rabbit, pigmented rabbit, human, porcine, and bovine eyes wa...

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Autori principali: Kadam, Rajendra S., Cheruvu, Narayan P. S., Edelhauser, Henry F., Kompella, Uday B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176076/
https://ncbi.nlm.nih.gov/pubmed/21282583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6233
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