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Sclera-Choroid-RPE Transport of Eight β-Blockers in Human, Bovine, Porcine, Rabbit, and Rat Models

PURPOSE. To determine the influence of drug lipophilicity, ocular pigmentation, and species differences on transscleral solute transport. METHODS. The transport of eight β-blockers across excised sclera/sclera-choroid-RPE (SCRPE) of albino rabbit, pigmented rabbit, human, porcine, and bovine eyes wa...

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Detalhes bibliográficos
Main Authors: Kadam, Rajendra S., Cheruvu, Narayan P. S., Edelhauser, Henry F., Kompella, Uday B.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176076/
https://ncbi.nlm.nih.gov/pubmed/21282583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6233
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