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Polymerase chain reaction: replication errors and reliability of gene diagnosis.

The impact of replication errors on the reliability of polymerase chain reaction (PCR) data is studied theoretically. Practical applications of our results to RFLP analysis and oligonucleotide probing confirm that for practical purposes replication errors can be neglected if a large number of starti...

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Detalhes bibliográficos
Main Authors: Krawczak, M, Reiss, J, Schmidtke, J, Rösler, U
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317589/
https://ncbi.nlm.nih.gov/pubmed/2565023
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