Early-Onset Chronic Obstructive Pulmonary Disease Is Associated with Female Sex, Maternal Factors, and African American Race in the COPDGene Study

Rationale: The characterization of young adults who develop late-onset diseases may augment the detection of novel genes and promote new pathogenic insights. Methods: We analyzed data from 2,500 individuals of African and European ancestry in the COPDGene Study. Subjects with severe, early-onset chr...

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Hlavní autoři: Foreman, Marilyn G., Zhang, Lening, Murphy, James, Hansel, Nadia N., Make, Barry, Hokanson, John E., Washko, George, Regan, Elizabeth A., Crapo, James D., Silverman, Edwin K., DeMeo, Dawn L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175544/
https://ncbi.nlm.nih.gov/pubmed/21562134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201011-1928OC
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