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Efficient Synthesis and Evaluation of Quorum Sensing Modulators Using Small Molecule Macroarrays

[Image: see text] A method for the synthesis of small molecule macroarrays of N-acylated L-homoserine lactones (AHLs) is reported. A focused library of AHLs was constructed, and the macroarray platform was found to be compatible with both solution and agar-overlay assays using quorum-sensing (QS) re...

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Bibliographic Details
Main Authors: Praneenararat, Thanit, Geske, Grant D., Blackwell, Helen E.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175425/
https://ncbi.nlm.nih.gov/pubmed/19743816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901871y
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