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The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures

Non-viral gene delivery vectors were developed for efficient gene transfer to hard to transfect mouse mammary epithelial cells. Ten modified versions of the same base poly(beta-amino ester), poly(1,4-butanediol diacrylate-co-5-amino-1-pentanol), were tested in both traditional 2-D monolayer and in 3...

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Detalhes bibliográficos
Main Authors: Bhise, Nupura S., Gray, Ryan S., Sunshine, Joel C., Htet, Soe, Ewald, Andrew J., Green, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175420/
https://ncbi.nlm.nih.gov/pubmed/20674001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.07.023
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