Integration host factor (IHF) stimulates binding of the gpNu1 subunit of lambda terminase to cos DNA.
The lambda terminase enzyme binds to the cohesive end sites (cos) of multimeric replicating lambda DNA and introduces staggered nicks to regenerate the 12 bp single-stranded cohesive ends of the mature phage genome. In vitro this endonucleolytic cleavage requires spermidine, magnesium ions, ATP and...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1989
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2522621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.5.2005 |
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