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Addition of DNase Improves the In Vitro Activity of Antifungal Drugs against Candida albicans Biofilms

BACKGROUND: Cells within Candida albicans biofilms display decreased susceptibility to most clinically used antifungal agents. We recently demonstrated that extracellular DNA (eDNA) plays an important role in biofilm integrity, as a component of the biofilm matrix. OBJECTIVE: To gain insight into th...

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Detalhes bibliográficos
Main Authors: Martins, Margarida, Henriques, Mariana, Lopez-Ribot, José L., Oliveira, Rosário
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175262/
https://ncbi.nlm.nih.gov/pubmed/21668524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1439-0507.2011.02047.x
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