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Oligothymidylates covalently linked to an acridine derivative and with modified phosphodiester backbone: circular dichroism studies of their interactions with complementary sequences.

Oligothymidylates involving alternating alkyl phosphotriester-phosphodiester or methylphosphonate-phosphodiester backbones and covalently linked to an acridine derivative have been studied using circular dichroism. Two isomers with the same diastereoisomeric configuration for all the phosphotriester...

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Main Authors: Durand, M, Maurizot, J C, Asseline, U, Barbier, C, Thuong, N T, Hélène, C
格式: Artigo
語言:Inglês
出版: 1989
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC317525/
https://ncbi.nlm.nih.gov/pubmed/2928108
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