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Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever
BACKGROUND: MEFV mutations and decreased expression level of the gene are related to FMF pathology. DNA methylation at CpG islands is a well-known mechanism for transcriptional silencing. MEFV has a CpG island, spanning a part of the first intron and the whole of the second exon of the gene covering...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175150/ https://ncbi.nlm.nih.gov/pubmed/21819621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-105 |
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