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Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever

BACKGROUND: MEFV mutations and decreased expression level of the gene are related to FMF pathology. DNA methylation at CpG islands is a well-known mechanism for transcriptional silencing. MEFV has a CpG island, spanning a part of the first intron and the whole of the second exon of the gene covering...

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Bibliografski detalji
Glavni autori: Kirectepe, Asli K, Kasapcopur, Ozgur, Arisoy, Nil, Celikyapi Erdem, Gokce, Hatemi, Gulen, Ozdogan, Huri, Tahir Turanli, Eda
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175150/
https://ncbi.nlm.nih.gov/pubmed/21819621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-105
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