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Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges

An increasing number of anti-cancer therapeutic agents target specific mutant proteins that are expressed by many different tumor types. Recent evidence suggests that the selection of patients whose tumors harbor specific genetic alterations identifies the subset of patients that are most likely to...

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Detalhes bibliográficos
Main Authors: MacConaill, Laura E., Van Hummelen, Paul, Meyerson, Matthew, Hahn, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175123/
https://ncbi.nlm.nih.gov/pubmed/21935500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0110
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