Plasmodium falciparum-Infected Erythrocytes and IL-12/IL-18 Induce Diverse Transcriptomes in Human NK Cells: IFN-α/β Pathway versus TREM Signaling

The protective immunity of natural killer (NK) cells against malarial infections is thought to be due to early production of type II interferon (IFN) and possibly direct NK cell cytotoxicity. To better understand this mechanism, a microarray analysis was conducted on NK cells from healthy donors PBM...

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Bibliographic Details
Main Authors: Grangeiro de Carvalho, Elisandra, Bonin, Michael, Kremsner, Peter G., Kun, Jürgen F. J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174986/
https://ncbi.nlm.nih.gov/pubmed/21949811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024963
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