Toll-Like Receptor 4 Is a Regulator of Monocyte and Electroencephalographic Responses to Sleep Loss

STUDY OBJECTIVES: Sleep loss triggers changes in inflammatory signaling pathways in the brain and periphery. The mechanisms that underlie these changes are ill-defined. The Toll-like receptor 4 (TLR4) activates inflammatory signaling cascades in response to endogenous and pathogen-associated ligands...

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Bibliographic Details
Main Authors: Wisor, Jonathan P., Clegern, William C., Schmidt, Michelle A.
Format: Artigo
Language:Inglês
Published: Associated Professional Sleep Societies, LLC 2011
Subjects:
Toll-Like Receptor 4 and Sleep Loss
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174835/
https://ncbi.nlm.nih.gov/pubmed/21966065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/SLEEP.1274
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