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TGF-β(2) reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells

Exhaled NO (eNO) is a potential noninvasive biomarker of inflammation in asthma. The significant intersubject variability of eNO within clinically similar patients has contributed to its limited clinical application. Arginase and NO synthase (NOS) utilize the same substrate (l-arginine) and contribu...

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Detalhes bibliográficos
Main Authors: Jiang, Jingjing, George, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174748/
https://ncbi.nlm.nih.gov/pubmed/21685242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00464.2010
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