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Connective tissue growth factor acts within both endothelial cells and β cells to promote proliferation of developing β cells

Type 1 and type 2 diabetes result from an absolute or relative reduction in functional β-cell mass. One approach to replacing lost β-cell mass is transplantation of cadaveric islets; however, this approach is limited by lack of adequate donor tissue. Therefore, there is much interest in identifying...

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Hlavní autoři: Guney, Michelle A., Petersen, Christine P., Boustani, Andre, Duncan, Matthew R., Gunasekaran, Uma, Menon, Renuka, Warfield, Courtney, Grotendorst, Gary R., Means, Anna L., Economides, Aris N., Gannon, Maureen
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174622/
https://ncbi.nlm.nih.gov/pubmed/21876171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100072108
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