Insights into Krabbe disease from structures of galactocerebrosidase

Krabbe disease is a devastating neurodegenerative disease characterized by widespread demyelination that is caused by defects in the enzyme galactocerebrosidase (GALC). Disease-causing mutations have been identified throughout the GALC gene. However, a molecular understanding of the effect of these...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Deane, Janet E., Graham, Stephen C., Kim, Nee Na, Stein, Penelope E., McNair, Rosamund, Cachón-González, M. Begoña, Cox, Timothy M., Read, Randy J.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174575/
https://ncbi.nlm.nih.gov/pubmed/21876145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105639108
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים