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Hypoxia. Cross talk between oxygen sensing and the cell cycle machinery
A fundamental physiological property of mammalian cells is the regulation of proliferation according to O(2) availability. Progression through the cell cycle is inhibited under hypoxic conditions in many, but not all, cell types, and this G1 arrest is dependent on hypoxia-inducible factor (HIF) 1α....
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| Natura: | Artigo |
| Lingua: | Inglês |
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American Physiological Society
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174572/ https://ncbi.nlm.nih.gov/pubmed/21677261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00176.2011 |
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