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Calcium-dependent inhibition of adrenal TREK-1 channels by angiotensin II and ionomycin

Bovine adrenocortical cells express bTREK-1 K(+) (bovine KCNK2) channels that are inhibited by ANG II through a Gq-coupled receptor by separate Ca(2+) and ATP hydrolysis-dependent signaling pathways. Whole cell and single patch clamp recording from adrenal zona fasciculata (AZF) cells were used to c...

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Autori principali: Enyeart, John J., Liu, Haiyan, Enyeart, Judith A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174564/
https://ncbi.nlm.nih.gov/pubmed/21613605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00117.2011
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