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HYPERCALCEMIA REDUCES PLASMA RENIN VIA PARATHYROID HORMONE, RENAL INTERSTITIAL CALCIUM AND THE CALCIUM-SENSING RECEPTOR

Acute hypercalcemia inhibits plasma renin activity. How this occurs is unknown. We hypothesized that acute hypercalcemia inhibits plasma renin activity via the calcium-sensing receptor due to parathyroid hormone-mediated increases in renal cortical interstitial calcium via TRPV5. To test our hypothe...

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Detalhes bibliográficos
Main Authors: Atchison, Douglas K., Harding, Pamela, Beierwaltes, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174336/
https://ncbi.nlm.nih.gov/pubmed/21825222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.172890
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