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Tuning arousal with optogenetic modulation of locus coeruleus neurons

Neural activity in the noradrenergic locus coeruleus correlates with periods of wakefulness and arousal. However, whether tonic or phasic activity in these neurons is necessary or sufficient to induce behavioral state transitions and promote long-term arousal is unresolved. We used optogenetic tools...

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Autors principals: Carter, Matthew E., Yizhar, Ofer, Chikahisa, Sachiko, Nguyen, Hieu, Adamantidis, Antoine, Nishino, Seiji, Deisseroth, Karl, de Lecea, Luis
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174240/
https://ncbi.nlm.nih.gov/pubmed/21037585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2682
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