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HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model

Infection and dissemination of HIV-1 through the female body after vaginal intercourse depends on the activation/differentiation status of mucosal CD4 T cells. Here, we investigated this status and the susceptibility to HIV-1 infection of human cervico-vaginal tissue ex vivo. We found that virtually...

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Bibliographic Details
Main Authors: Saba, Elisa, Grivel, Jean-Charles, Vanpouille, Christophe, Brichacek, Beda, Fitzgerald, Wendy, Margolis, Leonid, Lisco, Andrea
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173980/
https://ncbi.nlm.nih.gov/pubmed/20147895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.2
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