FUNCTIONAL GAP JUNCTIONS ACCUMULATE AT THE IMMUNOLOGICAL SYNAPSE AND CONTRIBUTE TO T CELL ACTIVATION

Gap junction (GJ) mediate intercellular communication through linked hemichannels from each of two adjacent cells. Using human and mouse models we show that connexin 43 (Cx43), the main GJ protein in the immune system, was recruited to the immunological synapse during T cell priming as both GJs and...

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Autores principales: Mendoza-Naranjo, Ariadna, Bouma, Gerben, Pereda, Cristian, Ramírez, Marcos, Webb, Kevin F., Tittarelli, Andrés, López, Mercedes N., Kalergis, Alexis M., Thrasher, Adrian J., Becker, David L., Salazar-Onfray, Flavio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173876/
https://ncbi.nlm.nih.gov/pubmed/21844382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100378
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