ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association

RNAi screening for kinases regulating the functional organization of the early secretory pathway in Drosophila S2 cells has identified the atypical Mitotic-Associated Protein Kinase (MAPK) Extracellularly regulated kinase 7 (ERK7) as a new modulator. We found that ERK7 negatively regulates secretion...

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Main Authors: Zacharogianni, Margarita, Kondylis, Vangelis, Tang, Yang, Farhan, Hesso, Xanthakis, Despina, Fuchs, Florian, Boutros, Michael, Rabouille, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173787/
https://ncbi.nlm.nih.gov/pubmed/21847093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.253
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