PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

Wnt signalling is an evolutionarily conserved pathway that directs cell-fate determination and morphogenesis during metazoan development. Wnt ligands are secreted glycoproteins that act at a distance causing a wide range of cellular responses from stem cell maintenance to cell death and cell prolife...

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Bibliographic Details
Main Authors: Peradziryi, Hanna, Kaplan, Nicole A, Podleschny, Martina, Liu, Xiaoping, Wehner, Peter, Borchers, Annette, Tolwinski, Nicholas S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173783/
https://ncbi.nlm.nih.gov/pubmed/21772251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.236
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