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Inhibition of protein-protein interactions with low molecular weight compounds

An overview of issues associated with the design and development of low molecular weight inhibitors of protein-protein interactions is presented. Areas discussed include information on the nature of protein-protein interfaces, methods to characterize those interfaces and methods by which that inform...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matthews, Marilyn M., Weber, David J., Shapiro, Paul S., Coop, Andrew, MacKerell, Alexander D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173769/
https://ncbi.nlm.nih.gov/pubmed/21927717
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