Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

Lysosomes are cellular organelles primarily involved in degradation and recycling processes. During lysosomal exocytosis, a Ca(2+)-regulated process, lysosomes are docked to the cell surface and fuse with the plasma membrane (PM), emptying their content outside the cell. This process has an importan...

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Hauptverfasser: Medina, Diego L., Fraldi, Alessandro, Bouche, Valentina, Annunziata, Fabio, Mansueto, Gelsomina, Spampanato, Carmine, Puri, Claudia, Pignata, Antonella, Martina, Jose A., Sardiello, Marco, Palmieri, Michela, Polishchuk, Roman, Puertollano, Rosa, Ballabio, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173716/
https://ncbi.nlm.nih.gov/pubmed/21889421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.07.016
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