CD8(+) CD28(−) and CD8(+) CD57(+) T cells and their role in health and disease

Chronic antigenic stimulation leads to gradual accumulation of late-differentiated, antigen-specific, oligoclonal T cells, particularly within the CD8(+) T-cell compartment. They are characterized by critically shortened telomeres, loss of CD28 and/or gain of CD57 expression and are defined as eithe...

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Bibliografiske detaljer
Main Authors: Strioga, Marius, Pasukoniene, Vita, Characiejus, Dainius
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2011
Fag:
Review Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173691/
https://ncbi.nlm.nih.gov/pubmed/21711350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03470.x
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