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Biophysical Mechanisms Underlying Outer Hair Cell Loss Associated with a Shortened Tectorial Membrane

The tectorial membrane (TM) connects to the stereociliary bundles of outer hair cells (OHCs). Humans with an autosomal dominant C1509G mutation in alpha-tectorin, a protein constituent of the TM, are born with a partial hearing loss that worsens over time. The Tecta(C1509/+) transgenic mouse with th...

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Detalhes bibliográficos
Main Authors: Liu, Christopher C., Gao, Simon S., Yuan, Tao, Steele, Charles, Puria, Sunil, Oghalai, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173552/
https://ncbi.nlm.nih.gov/pubmed/21567249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-011-0269-0
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