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Regulation of basal LC20 phosphorylation by MYPT1 and CPI-17 in murine gastric antrum, gastric fundus, and proximal colon smooth muscles

BACKGROUND: Myosin light chain kinase (MLCK) and phosphatase (MLCP) govern myosin light chain (LC20) phosphorylation and smooth muscle contraction. Rho kinase (ROK) inhibits MLCP, resulting in greater LC20 phosphorylation and force generation at a given [Ca(2+)](i). Here, we investigate the role of...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bhetwal, Bhupal P., An, Chang Long, Fisher, Steven A., Perrino, Brian A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173524/
https://ncbi.nlm.nih.gov/pubmed/21883701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2011.01769.x
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