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Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe

BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but extremely severe cutaneous adverse drug reactions in which drug-specific associations with HLA-B alleles were described. OBJECTIVES: To investigate genetic association at a genome-wide level on a large sampl...

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Detalhes bibliográficos
Main Authors: Génin, Emmanuelle, Schumacher, Martin, Roujeau, Jean-Claude, Naldi, Luigi, Liss, Yvonne, Kazma, Rémi, Sekula, Peggy, Hovnanian, Alain, Mockenhaupt, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173287/
https://ncbi.nlm.nih.gov/pubmed/21801394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-6-52
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